Aptamer-conjugated liposome system for targeting MUC1-positive cancer: an in silico screening approach

Health Nanotechnology

Table 2 Characteristics of liposomes based on lipid molar ratio

Molar Ratio	PBS (ml)	Abs (Before)	Abs (After)	Encapsulation rate	Size (nm)	PDI
15:9:1.0	2	0.612	0.060	9.80%	47.79	0.164
15:9:1.5	2	0.595	0.086	14.45%	50.73	0.147
12:8:1.0	2	0.623	0.046	7.38%	51.60	0.161
12:8:1.5	2	0.602	0.111	18.44%	51.98	0.163
10:6:1.0	2	0.586	0.208	35.49%	75.05	0.106
10:6:1.5	2	0.620	0.455	73.39%	84.86	0.166

The table provides information on the molar ratios utilized for liposome synthesis. It also includes the absorption scores before and after purification of DOX encapsulation by liposome. Additionally, the table presents the encapsulation rate of DOX, the size of the liposomes, and their PDI scores. DOX Doxorubicin, PDI Poly Dispersity Index

ISSN: 2948-1937