Fig. 7
From: Optical imaging in biomedical research: guidelines and practical insights
Fast in vivo brain imaging with Er-RENPs@PMH-PEG in the NIR-IIb region. a Color photograph of a C57Bl/6 mouse (with hair shaved off) preceding NIR-IIb fluorescence imaging. b–d Time-course NIR-IIb brain fluorescence images (exposure time: 20 ms) showing the perfusion of RENPs into various cerebral vessels. The blood-flow velocities of cerebral vessels are given in c (scale bar corresponds to b–d: 2 mm). e, f Cerebral vascular image (exposure time: 20 ms) in NIR-IIb region with corresponding PCA overlaid image f showing arterial (red) and venous (blue) vessels. g SBR analysis of NIR-IIb cerebrovascular image d by plotting the cross-sectional intensity profiles. Copyright: ref [124], Nature Publishing Group 2017